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What Is The Largest Cell In The Human Body

What Is The Largest Cell In The Human Body? Cellular Giants

What is the largest cell in the human body? This question sparks curiosity and drives us to explore the common denominator of life in all living organisms. 

Cells are the building blocks of life, and the human body is composed of roughly 37.2 (give or take) trillions of them.

Within our bodies, each cell has its unique structure and function. While most cells are relatively small, one stands out as the largest. 

But which one is it? We believe that your curiosity has brought you here, and in a few, you’ll get the right answer and more information on the same. So make sure to read to the end to learn more.

What Is The Largest Cell In The Human Body?

The ovum, the female gamete, is the largest cell in the human body and measures 0.1mm in diameter. And why is it so big? You may wonder. 

Its large size is necessary to accommodate the essential components for successful fertilization and early embryonic development. 

As you know, the ovum is fertilized by the sperm, meaning it has to be big enough to take in the sperm cell. And guess what? You can see the human egg with the naked eye without using a microscope!

What Is The Ovum Made Of?

The ovum is made up of various components that play essential roles in the development of an embryo. At its core, the ovum contains a central nucleus housing the female’s genetic material. 

The nucleus of the ovum carries the genetic information that will shape the characteristics and traits of the offspring. It contains strands of DNA that encode the instructions for building proteins and regulating various biological processes within the developing embryo. 

The genetic material within the ovum combines with that of the sperm during fertilization, resulting in a unique combination of genes that will determine factors such as eye color, hair texture, and height.

Surrounding the nucleus is cell plasma, sometimes called the yolk, which contains vital nutritional elements necessary for the growth and development of the egg cell. 

This yolk is rich in lipids, polysaccharides, proteins, and other vital substances required for cellular growth and division. These nutrients fuel the metabolic processes within the ovum and support its development into an embryo.

What Is The Function Of The Ovum?

The primary function of the ovum is to transport the genetic material provided by the female gamete in the form of chromosomes. It facilitates fertilization by creating a suitable environment for the interaction with sperm. 

Additionally, the ovum serves as a source of nourishment for the developing embryo until it implants itself in the uterus, at which point the placenta assumes responsibility for sustenance.

When the egg is not fertilized within 24 hours of its release, it begins to undergo degeneration. Once the ovum is fertilized, it undergoes a series of cell divisions. 

In the early stages of development, if the fertilized egg splits into two, it leads to the formation of identical twins. On the other hand, if the division of the cell is incomplete, it results in the birth of Siamese twins who are physically joined together. 

Another scenario is when two separate eggs are released and fertilized independently, resulting in fraternal twins.

The Smallest Cell In The Human Body

Now that you already know the largest cell in your body, it is only natural to be curious about its polar opposite. 

So, what exactly is the smallest cell in our bodies? In our relentless pursuit of knowledge, we leave no stone unturned, so let’s discuss this matter.

What is the smallest cell in the human body? The smallest cell in the human body is the sperm cell. The size of the head of a sperm cell is approximately 4 micrometers, which is comparable to the size of a red blood cell (RBC).

Sperm Cell Vs Ovum

Now, let’s see how the largest cell in the human body compares to the smallest cell in the human body.

Sperm Ovum
Structure Streamlined, with a head, mid-piece, and tail.  Rounded, with a large nucleus and surrounding cytoplasm
Function Carries genetic material from male to female during fertilization Carries genetic material from females to support embryo development
Mobility Equipped with a flagellum for swimming towards the egg Non-motile, unable to move independently
Lifespan Can survive for a few days Can survive for around 12 to 24 hours after ovulation
Number produced Millions are produced in each ejaculation One ovum is released during each menstrual cycle
Specializations The acrosome on the head contains enzymes for egg penetration Contains nutrients to support the initial stages of embryo development
Genetic Contribution Contributes half of the genetic material needed Contributes the other half of the genetic material
Fertilization Process Penetrates the egg’s protective layers and fuses with its membrane to form a zygote Engulfs the sperm, forming a zygote with combined genetic material

What Is A Cell?

A cell is the basic structural and functional unit of all living organisms. It is the smallest unit of life that can perform all the necessary functions required for survival. Cells vary in size, shape, and function but share certain characteristics. 

They are enclosed by a plasma membrane, which separates the cell from its environment and regulates the flow of substances in and out of the cell. 

Inside the cell, there is a nucleus that contains genetic material, as well as various organelles that carry out specific functions. 

Cells are responsible for metabolism, growth, reproduction, and response to stimuli. The human body contains the following common organelles.

  • Cytoplasm – The primary function of the cytoplasm is to provide a medium for the cell’s organelles to carry out their specific functions. 

It also aids in moving molecules within the cell through cytoplasmic streaming. Additionally, the cytoplasm plays a role in cellular metabolism by providing a site for various biochemical reactions.

  • The nucleus contains the cell’s DNA, which carries the genetic information necessary for cellular function and reproduction. The main function of the nucleus is to regulate gene expression, which involves controlling the production of proteins.

It transcribes DNA into messenger RNA (mRNA), which is then transported out of the nucleus and into the cytoplasm, where ribosomes can translate it into proteins.

  • Endoplasmic reticulum – The endoplasmic reticulum (ER) is a network of membranes connected to the nuclear envelope. It can be divided into two regions: rough ER and smooth ER. 

The rough ER contains ribosomes on its surface and is involved in protein synthesis and processing. The smooth ER, on the other hand, is involved in lipid metabolism, calcium storage, and detoxification of drugs and toxins.

  • Ribosomes are small organelles that are either free-floating in the cytoplasm or attached to the rough ER. Their main function is protein synthesis. 

They read the mRNA produced by the nucleus and use it as a template to assemble amino acids into polypeptide chains, which then fold into functional proteins. Ribosomes are essential for cellular growth, repair, and maintenance.

  • Lysosomes and peroxisomes contain enzymes that break down waste materials, cellular debris, and foreign particles such as bacteria or viruses. They recycle cellular components through a process called autophagy. 

On the other hand, peroxisomes contain enzymes that break down toxic substances such as hydrogen peroxide and fatty acids. They are also involved in lipid metabolism and detoxification.

  • Cytoskeleton – The cytoskeleton is a network of protein filaments that provides the cell support, shape, and organization. It comprises three main components: microtubules, microfilaments, and intermediate filaments. 

Microtubules provide structural support and act as tracks for intracellular transport. Microfilaments are involved in cell movement, contraction, and support of cellular extensions such as microvilli or cilia. 

Intermediate filaments provide mechanical strength to cells and help anchor organelles in place.

  • Plasma membrane – The plasma membrane is a thin barrier that separates the cell’s interior from its external environment. 

Its main function is to regulate the movement of substances into and out of the cell. It is selectively permeable, allowing certain molecules to enter or exit while restricting others.

  • Mitochondria – Mitochondria are responsible for producing energy through cellular respiration. They have their DNA and can replicate independently from the nucleus.

Mitochondria generate adenosine triphosphate (ATP), the energy source for cellular activities.


What is the largest cell in the human body? The largest cell in the human body is the ovum. It is approximately 0.1 millimeters in diameter, making it visible to the naked eye. 

The ovum plays a crucial role in reproduction, fusing with a sperm cell during fertilization to form a zygote. This zygote then develops into an embryo and, eventually, a fetus.

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